A systematic review of the phytochemical profile and medicinal significance of Evolvulus alsinoides

Cheekavolu C, Karnam N, Choudhary N, Sangeeta BSR, Mavillapalli RC

Pdf Page Numbers :- 223-228

Chakrapani Cheekavolu¹, Nithya Karnam^2,*, Naiyma Choudhary³, Sangeeta BSR⁴ and Rishitha Chowdary Mavillapalli⁵

¹Department of Pharmacology, Karpagam Faculty of Medical Science and Research, Ottakalmandapam, Coimbatore, Tamil Nadu 641032, India

²Department of Pharmacology, Sri Venkateswaraa Medical College & Hospital, Sri Venkateswaraa University, Red Hills, Chennai, Tamil Nadu 600067, India

³Department of Pharmacology, MVJ Medical College and Research Hospital, Bangalore - 562114, Karnataka, India

⁴Department of Medical Surgical Nursing, Symbiosis College of Nursing, Faculty of Nursing, Symbiosis International University, Lavale, Pune

⁵Department of Pharmacognosy, Faculty of Pharmacy, Sri Ramachandra University, Chennai, Tamil Nadu 600116, India

*Corresponding author: Dr. Karnam Nithya, Associate professor, Department of Pharmacology, Sri Venkateswaraa Medical College & Hospital, Sri Venkateswaraa University, Red Hills, Chennai, Tamil Nadu 600067, India. Email: nithyasree13@gmail.com

Received 5 December 2024; Revised 4 March 2025; Accepted 11 March 2025; Published 19 March 2025

Citation: Cheekavolu C, Karnam N, Choudhary N, Sangeeta BSR, Mavillapalli RC. A systematic review of the phytochemical profile and medicinal significance of Evolvulus alsinoides. J Med Sci Res. 2025; 13(2):223-228. DOI: http://dx.doi.org/10.17727/JMSR.2024/13-39

Copyright: © 2025 Cheekavolu C et al. Published by KIMS Foundation and Research Center. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Abstract

Background: The perennial herb Evolvulus alsinoides L., sometimes called "Vishnukranthi" or "Shankhpushpi," belongs to the Convolvulaceae family. Traditional medicine utilises the entire plant and its various parts to treat multiple ailments, including stomach ulcers. This review aimed to analyse the phytochemical constituents of extracts of E. alsinoides and highlights its medicinal importance.

Methods: This systematic review was conducted using search strings such as “Shankhpushpi” and “Evolvulus alsinoides Linn,” with data extracted from experimental studies published between June 2019 and 2024 across PubMed, medRxiv, Scopus, and Google Scholar databases.

Results: In this study, a total of 174 articles were generated from the search string, and two authors were involved in screening the articles as per inclusion and exclusion criteria. Finally, 25 articles were included and 149 articles were excluded. The phytochemical constituents of different extraction methods and medicinal properties were discussed in this review.

Conclusion: E. alsinoides exhibits nootropic, anxiolytic, and memory-enhancing effects, supports respiratory and neurological health, and shows immunomodulatory and hepatoprotective properties, validating its traditional use as a potent therapeutic herb for multiple ailments.

Keywords: Evolvulus alsinoides; medicinal uses; pharmacological properties; phytochemical analysis; methanolic extract; bioactive compounds