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What is this condition?

What is the sign to be elicited?

What is the severity of illness score and describe?

Figure a,b,c,d: 30-year-old male consulted orthopaedician for joint pains and he was given allopurinol. Patient developed these lesions within 2 days of medication.

Answer for the medical quiz – 30-years-old male developed lesions

Answer for question 1: Toxic epidermal necrolysis

Answer for question 2: Nikolsky's sign

Answer for question 3: The SCORTEN score (a severity-of-illness score for toxic epidermal necrolysis) calculates the risk for death in both SJS and TEN based on the following variables:

• Age >40 years
• Malignancy
• Heart rate >120
• Initial percentage of epidermal detachment >10%
• Blood urea nitrogen (BUN) level >10 mmol/L
• Serum glucose level >14 mmol/L
• Bicarbonate level < 20 mmol/L

Each variable is assigned a value of 1 point. Mortality rates are as follows:

• 0-1 points, ≥ 3.2%
• 2 points, ≥12.1%
• 3 points, ≥35.3%
• 4 points, ≥58.3%
• 5 or more points, ≥90%